Phylum Ascomycota Caval.-Sm. (1998) - sac fungi
   Subphylum Pezizomycotina O.E. Erikss. & Winka (1997)
     Class Eurotiomycetes O.E. Erikss. & Winka (1997)
       Subclass Chaetothyriomycetidae Doweld (2001)
         Order Pyrenulales Fink ex D.Hawksw. & O.E. Erikss. (1986)
           Family Pyrenulaceae Rabenh. (1870)
             01 Genus Acrocordiella O.E. Erikss. (1982)
             02 Genus Anthracothecium Hampe ex A.Massal. (1860)
             03 Genus Clypeopyrenis Aptroot (1991)
             04 Genus Distopyrenis Aptroot (1991)
             05 Genus Granulopyrenis Aptroot (1991)
             06 ?Genus Lacrymospora Aptroot (1991)
             07 Genus Lithothelium Müll.Arg. (1885)
             08 Genus Mazaediothecium Aptroot (1991)
             09 Genus Parapyrenis Aptroot (1991)
             10 Genus Polypyrenula D.Hawksw. (1985)
             11 Genus Pyrenographa Aptroot (1991)
             12 Genus Pyrenowilmsia R.C. Harris & Aptroot (1991)
             13 Genus Pyrenula Ach. (1814), nom. cons.
             14 Genus Pyrgillus Nyl. (1858)
             15 Genus Sulcopyrenula H. Harada (1999)