Phylum Amoebozoa Lühe, 1913
   Subphylum Lobosa Carpenter, 1861 see Infraphylum Lobosa Carpenter, 1861
     Class Discosea Cavalier-Smith, 2004
       Subclass Longamoebia Cavalier-Smith & Smirnov, 2011
         Order Centramoebida Rogerson & Patterson, 2002
           Family Acanthamoebidae Sawyer & Griffin, 1975
             1 Genus Acanthamoeba Volkonsky, 1931
             2 Genus Protacanthamoeba F.C. Page, 1981